Medical research dossiers for the teams deciding which innovations and discoveries to pursue.
We distill 100+ primary sources into one audited, decision-ready dossier — a generative thesis, 10+ forward-leading hypotheses, and the exact next experiments to run.
Months of gathering, assessment, and connection-making — done, traceable, and forward-looking. The answer, not the reading list.
One dossier. Five buyers. A different tab for each.
Investors & VCs
A dated catalyst calendar and a scored landscape to underwrite the thesis.
Biotech & R&D
A ready-made, falsifiable research agenda — the next experiments, prioritized.
Research firms
3–6 months of literature gathering and synthesis — done, audited, traceable.
Strategy & BD
Where each program wins or loses, on the axes that actually decide deals.
Regulators & payers
Every claim graded and traced to source, with the evidence standard made explicit.
About 21 working sheets. This is the value.
The figures above are in the research report. The workbook is the engine room — far more than traceability. (Exact sheets vary slightly by dossier.)
Workbook Guide
How to read it — scope, reconciliation, and the audit posture behind every number.
Claim Ledger
Every customer-facing claim, independently verified, framework-tagged and value-graded.
Source-Support Verdicts
An independent verdict per claim — with a verbatim excerpt pulled from the source.
Evidence Table
Every re-verified source — PMIDs, DOIs and trial IDs — resolved live, zero retracted.
Source-Quality Dashboard
The recalibrated grade distribution — honest about how strong the evidence really is.
Platform Scorecard
Each platform or approach scored against the dossier's controlling framework.
Framework-Axis Scorecard
Every program scored on the model's axes — where it wins, loses, and is mispriced.
Asset / Sponsor Tracker
Who's building what, with the reporting basis made explicit — designation ≠ approval.
Trial & Catalyst Tracker
Every relevant trial, its status, and the dated readout that moves the thesis.
Safety-Signal Tracker
The adverse signals and risks that quietly break otherwise-attractive theses.
Resistance / Failure-Mode Tracker
How each approach fails, and when — the escape routes and breakpoints.
Biomarker-to-Endpoint Map
Which surrogate licenses which claim — the bridge from signal to outcome.
Regulatory Tracker
The regulatory channel for each program; a designation is never an approval.
Domain Sub-System Tracker
The decisive sub-systems specific to the field — diagnostics, delivery, ecology.
Hypotheses Ledger
The falsifiable, dated hypotheses — each with the readout that would prove it wrong.
Most Valuable Next Studies
The highest-leverage de-risking experiments to run in 2026–2028.
Figure Source Map
Full lineage for every figure in the report — what it's built from.
Figure Attempt Ledger
The figure-generation log — no placeholders, nothing unaccounted for.
Verification & Search Log
The dated trail of every query the audit ran — the receipts behind the work.
Excluded-Claim Dispositions
Every claim we considered and cut — with the reason. The work, including what didn't make it.
Salvage Ledger
The reuse / sharpen / fix / recover / add decisions behind the final set.
The actual Precision AMR workbook.
Every sheet from the Precision AMR dossier's evidence workbook, with its real rows. Click the tabs at the bottom to move between all 22.
3–6 months of research, distilled into 10+ forward-looking hypotheses and the best next steps.
Independently audited, every claim traceable, and built to act on — today.
Sources, synthesized
Every relevant primary source within the topic — reviewed, studied, graded, and connected, not just listed.
Forward hypotheses
Falsifiable, dated predictions and the exact next experiments — a research agenda you can adopt on Monday.
Connections others miss
A convergence map of non-obvious couplings — insight siloed, single-lane analysis can't reach.
This is a real dossier — not a brochure.
Precision AMR Countermeasures
- DOSSIER77 pages, 31 figures. A generative thesis — the escapable-vs-cornered law — with a Decision Snapshot and Buyer Decision Cheat Sheet built in.
- WORKBOOK22 sheets. A dated 31-trial catalyst tracker, scored landscape, 9 next-experiments, and 90 claims each with a verbatim source excerpt.
- AUDIT92.4 / 100, release-ready. 138 sources resolved live, zero retractions — shipped in the box.
- HYPOTHESES12 falsifiable, dated. Each with the readout that would prove it wrong.
Real figures. Real data. Yours to use.
Falsifiable hypotheses, dated and disconfirmable.
Real examples from the dossiers — each with the readout that would prove it wrong.
A cost-locked combination suppresses resistance longer than any single agent — and longer than a novel AI-designed monotherapy.
A personalized vaccine changes outcomes in a cold tumor selected by ctDNA.
Microbiome-sparing is a safety intervention, not only stewardship — a narrow-spectrum regimen cuts secondary infection and AKI at equal cure.
Provable, forward-looking, built to be used.
Click any card to see a concrete example.
Provable, not plausible.
Every citation resolved live; an independent agent re-checks every figure and load-bearing sentence and signs a final verdict.
Forward-looking, not a recap.
Not a literature review. New, falsifiable hypotheses grounded on the latest developments.
A thesis, not a landscape.
One controlling idea that tells you which programs win and why.
Connections siloed analysis misses.
A convergence map of ~7 non-obvious couplings per dossier.
Nine domains. Ten founding dossiers.
Click a domain to open its dossiers.
Oncology
Engineering the therapeutic index, and MRD-guided recurrence prevention.
2 dossiersImmunology
Durable immune reset in autoimmune cell therapy.
1 dossierGene Therapy
The durability–immunogenicity–delivery triad, in vivo.
1 dossierCardiovascular
Genetic cardiomyopathy precision therapies.
1 dossierInfectious Disease
Cornering antimicrobial resistance.
1 dossierRare Diseases
From unsolved variant to programmable therapy.
1 dossierDigital Health
Why AI accuracy fails to translate — and the fix.
1 dossierNeurology
Long-term brain-implant stability.
1 dossierEmerging Med Tech
Clinical-grade liver & kidney biofabrication.
1 dossierA research swarm,
then an adversarial audit.
A reasoning CEO agent plans, gathers and debates evidence across hundreds of sources, and composes a governed deliverable — then an independent auditor tries to break it before release.
We don't ask you to trust the output.
We hand you the audit that tested it.
Every citation resolved live, every figure checked, the thesis itself tested — corrected, re-verified, scored before release. Typically ~92/100, release-ready, zero fabricated citations.
Buy once. Yours to keep.
Founding-launch pricing — locked for early licensees, rising as the library deepens.
One-time purchase · perpetual license · yours to keep · not a subscription